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Woman’s cancer killed by measles virus
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16 May ’14 - 11:40 am
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Good for her, when I hear stories like this, I wonder how the idea came about,

Hey Joe, what do you think if we give her enough measles virus for 10 million people?

Great scott, that might just work!

 

Her name is Stacy Erholtz. For years, the 50-year-old mom from Pequot Lakes, Minn., battled myeloma, a blood cancer that affects bone marrow. She had few options left.

She had been through chemotherapy treatments and two stem cell transplants. But it wasn’t enough. Soon, scans showed she had tumors growing all over her body.

One grew on her forehead, destroying a bone in her skull and pushing on her brain. Her children named it Evan, her doctor said. Cancer had infiltrated her bone marrow.

A nurse uses a syringe to prepare an injection of the combined Measles Mumps and Rubella (MMR) vaccination at an MMR drop-in clinic at Neath Port Talbot Hospital near Swansea in south Wales on April 20, 2013. Public health officials said on April 19 they were investigating the first suspected death from measles in Britain in five years, after an outbreak blamed on a campaign against vaccinations. More than 800 people have contracted the highly contagious disease in Wales in the past six months, centred around the southern city of Swansea. Marion Lyons, director of health protection for Wales, said it had now been confirmed that a 25-year-old man from Swansea who died on April 18 had measles, a full postmortem will be conducted to determine cause of death. AFP PHOTO / GEOFF CADDICK        (Photo credit should read GEOFF CADDICK/AFP/Getty Images)

A nurse uses a syringe to prepare an injection of the combined Measles Mumps and Rubella (MMR) vaccination at an MMR drop-in clinic in 2013. (GEOFF CADDICK/AFP/Getty Images)

So, as part of a two-patient clinical trial, doctors at theMayo Clinic injected Erholtz with 100 billion units of the measles virus – enough to inoculate 10 million people.

Her doctor said they were entering the unknown.

Five minutes into the hour-long process, Erholtz got a terrible headache. Two hours later, she started shaking and vomiting. Her temperature hit 105 degrees, Stephen Russell, the lead researcher on the case, told The Washington Post early Thursday morning.

“Thirty-six hours after the virus infusion was finished, she told me, ‘Evan has started shrinking,’” Russell said. Over the next several weeks, the tumor on her forehead disappeared completely and, over time, the other tumors in her body did, too.

Russell said he and his team had engineered the virus to make it more suitable for cancer therapy. And, after just one dose of it, Erholtz’s cancer went into remission. She has been completely cleared of the disease, Russell wrote in Mayo Clinic Proceedings. Though, in this trial, the treatments were successful on only one of the two patients.

And Tanios Bekaii-Saab, a researcher at James Cancer Hospital and Solove Research Institute in Ohio, said the study must be confirmed in large randomized clinical trials — where many hopes get dashed, the Minneapolis Star Tribune reported.

“Unless we get to the third stage of development, we are cautiously optimistic,” he said.

http://www.washingto.....ted-trial/

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